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2020 2
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Page 1
Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Flint AC, Mitchell DK, Angus SP, Smith AE, Bessler W, Jiang L, Mang H, Li X, Lu Q, Rodriguez B, Sandusky GE, Masters AR, Zhang C, Dang P, Koenig J, Johnson GL, Shen W, Liu J, Aggarwal A, Donoho GP, Willard MD, Bhagwat SV, Clapp DW, Rhodes SD. Flint AC, et al. Among authors: mitchell dk. Clin Cancer Res. 2023 Sep 1;29(17):3438-3456. doi: 10.1158/1078-0432.CCR-22-2854. Clin Cancer Res. 2023. PMID: 37406085 Free PMC article.
Genetic Testing Guidelines Impact Care in Newborns with Congenital Heart Defects.
Durbin MD, Fairman K, Helvaty LR, Huang M, Li M, Abreu D, Geddes GC, Helm BM, Landis BJ, McEntire A, Mitchell DK, Ware SM. Durbin MD, et al. Among authors: mitchell dk. J Pediatr. 2023 Sep;260:113495. doi: 10.1016/j.jpeds.2023.113495. Epub 2023 May 20. J Pediatr. 2023. PMID: 37211210 Free PMC article.
Spatial Gene-Expression Profiling Unveils Immuno-oncogenic Programs of NF1-Associated Peripheral Nerve Sheath Tumor Progression.
Mitchell DK, Burgess B, White EE, Smith AE, Sierra Potchanant EA, Mang H, Hickey BE, Lu Q, Qian S, Bessler W, Li X, Jiang L, Brewster K, Temm C, Horvai A, Albright EA, Fishel ML, Pratilas CA, Angus SP, Clapp DW, Rhodes SD. Mitchell DK, et al. Clin Cancer Res. 2024 Mar 1;30(5):1038-1053. doi: 10.1158/1078-0432.CCR-23-2548. Clin Cancer Res. 2024. PMID: 38127282
New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types.
Gampala S, Moon HR, Wireman R, Peil J, Kiran S, Mitchell DK, Brewster K, Mang H, Masters A, Bach C, Smith-Kinnamen W, Doud EH, Rai R, Mosley AL, Quinney SK, Clapp DW, Hamdouchi C, Wikel J, Zhang C, Han B, Georgiadis MM, Kelley MR, Fishel ML. Gampala S, et al. Among authors: mitchell dk. Pharmacol Res. 2024 Mar;201:107092. doi: 10.1016/j.phrs.2024.107092. Epub 2024 Feb 2. Pharmacol Res. 2024. PMID: 38311014 Free PMC article.
Rapid Genome Sequencing Shows Diagnostic Utility In Infants With Congenital Heart Defects.
Durbin MD, Helvaty LR, Posorske A, Zhang S, Huang M, Li M, Abreu D, Fairman K, Geddes GC, Helm BM, Landis BJ, McEntire A, Mitchell DK, Ware SM. Durbin MD, et al. Among authors: mitchell dk. Res Sq [Preprint]. 2024 Mar 20:rs.3.rs-3976548. doi: 10.21203/rs.3.rs-3976548/v1. Res Sq. 2024. PMID: 38562732 Free PMC article. Preprint.
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia.
Edwards DM, Mitchell DK, Abdul-Sater Z, Chan KK, Sun Z, Sheth A, He Y, Jiang L, Yuan J, Sharma R, Czader M, Chin PJ, Liu Y, de Cárcer G, Nalepa G, Broxmeyer HE, Clapp DW, Sierra Potchanant EA. Edwards DM, et al. Among authors: mitchell dk. Front Oncol. 2021 Nov 5;11:752933. doi: 10.3389/fonc.2021.752933. eCollection 2021. Front Oncol. 2021. PMID: 34804941 Free PMC article.
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1.
Mund JA, Park S, Smith AE, He Y, Jiang L, Hawley E, Roberson MJ, Mitchell DK, Abu-Sultanah M, Yuan J, Bessler WK, Sandusky G, Chen S, Zhang C, Rhodes SD, Clapp DW. Mund JA, et al. Among authors: mitchell dk. J Biol Chem. 2020 Jul 17;295(29):9948-9958. doi: 10.1074/jbc.RA119.010981. Epub 2020 May 29. J Biol Chem. 2020. PMID: 32471868 Free PMC article.
Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17.
Mund JA, Park S, Smith AE, He Y, Jiang L, Hawley E, Roberson MJ, Mitchell DK, Abu-Sultanah M, Yuan J, Bessler WK, Sandusky G, Chen S, Zhang C, Rhodes SD, Clapp DW. Mund JA, et al. Among authors: mitchell dk. J Biol Chem. 2020 Nov 13;295(46):15795. doi: 10.1074/jbc.AAC120.016426. J Biol Chem. 2020. PMID: 33188083 Free PMC article. No abstract available.
Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Flint AC, Mitchell DK, Angus SP, Smith AE, Bessler W, Jiang L, Mang H, Li X, Lu Q, Rodriguez B, Sandusky GE, Masters AR, Zhang C, Dang P, Koenig J, Johnson GL, Shen W, Liu J, Aggarwal A, Donoho GP, Willard MD, Bhagwat SV, Clapp DW, Rhodes SD. Flint AC, et al. Among authors: mitchell dk. Clin Cancer Res. 2024 May 1;30(9):1992. doi: 10.1158/1078-0432.CCR-24-0635. Clin Cancer Res. 2024. PMID: 38690594 No abstract available.